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Disorder of Myelinating Cells


Research Directory

Disorder of Myelinating Cells


Disorder of Myelinating Cells

Myelin is the electrical insulation of neurons, and the correct myelination of our nervous system is absolutely vital for both the normal function and survival of neurons. Myelinating cells wrap layers of membrane around the axons of nerve cells, and this remarkable process both protects neurons and boosts the speed they can carry information around our nervous system. Myelination in our nervous systems is performed by two types of cell, oligodendrocytes in our central nervous system (CNS) and Schwann cells in our peripheral nervous system (PNS).

The inappropriate demyelination, proliferation or even death of myelinating cells in our nervous system causes many devastating clinical conditions such as multiple sclerosis, glial cell tumours (e.g. schwannomas) and peripheral demyelinating neuropathies. By studying changes in signally inside glial cells, both in normal development and disease, this allows us to define the role of specific pathways and develop clinical approaches to treat these conditions. 

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Further Information:

Please contact the Faculty Research Office

Research opportunities in this area:

Most groups provide research opportunities (including MPhil/PhD where available). Please get in touch with the contacts named above for further information.